|
" In vitro antifungal activity of Zataria multiflora essential oil, fluconazole and ciclopirox olamine against nonalbicans Candida species isolated from recurrent vulvovaginal candidiasis "
M.AL Esfandiary؛ Shahram Mahmoudi؛ Farideh zaini؛ Mahin Safara؛ mahmoud mahmoudi؛ A.R Farasat؛ A Sabokbar؛ S abbasi؛ Mohammad Ghahri؛ M.AM Esfandiary؛ Parivash Kordbacheh
2021/09/25
| Record Number
|
:
|
1502459
|
| Language of Document
|
:
|
English
|
| Main Entry
|
:
|
M.AL Esfandiary
|
| Title & Author
|
:
|
In vitro antifungal activity of Zataria multiflora essential oil, fluconazole and ciclopirox olamine against nonalbicans Candida species isolated from recurrent vulvovaginal candidiasis [electronic resources: essay]/ M.AL Esfandiary؛ Shahram Mahmoudi؛ Farideh zaini؛ Mahin Safara؛ mahmoud mahmoudi؛ A.R Farasat؛ A Sabokbar؛ S abbasi؛ Mohammad Ghahri؛ M.AM Esfandiary؛ Parivash Kordbacheh
|
| Piece Level
|
:
|
Journal of Mycology Research
|
| Notes Pertaining to Publication, Distribution, Etc.
|
:
|
June 2015
|
|
|
:
|
Original Articles
|
| Access Link
|
:
|
https://jmr.ut.ac.ir/article_54153.html
|
|
|
:
|
https://jmr.ut.ac.ir/article_54153_5cc5019b1838069f2a5268300cc0dd7e.pdf
|
| Summary or Abstract
|
:
|
The aim of the present study was to investigate the antifungal activity of Zatariamultiflora essential oil, fluconazole and ciclopirox olamine against 44 non-albicansCandida isolates from patients with recurrent vulvovaginal candidiasis. A set of C.glabrata (29 strains), C. krusei (3 stains) and C. patapsilosis (2 strains) were studiedusing Clinical and Laboratory Standards Institute (CLSI) broth macrodilution method.The results revealed that 33 isolates were resistant (MIC=64 μg/ml), 4 isolates weresusceptible (MIC≤ 8 μg/ml) and 7 isolates had dose-dependent susceptibility (MIC= 16,32 μg/ml) to fluconazole, respectively. With regard to fluconazole, high resistance ratewas observed in C .glabrata and C. krusei. However, ciclopirox olamine was found toinhibit the growth of all non-albicans Candida species (MIC≤8 μg/ml). In this study,favorable antifungal activity against non-albicans Candida species was obtained by Z.multiflora despite having a wide range of MICs (34875-139500 μg/ml). The resultsindicated that ciclopirox olamine and Z. multiflora might be promising in the treatment ofrecurrent vulvovaginal candidiasis.
|
| Topical Name Used as Subject
|
:
|
fluconazole
|
|
|
:
|
non-albicans candida spp
|
|
|
:
|
recurrent
|
|
|
:
|
ciclopirox olamine
|
| Personal Name - Alternative Intelectual Responsibility
|
:
|
A Sabokbar
|
|
|
:
|
A.R Farasat
|
|
|
:
|
Farideh zaini
|
|
|
:
|
M.AM Esfandiary
|
|
|
:
|
Mahin Safara
|
|
|
:
|
mahmoud mahmoudi
|
|
|
:
|
Mohammad Ghahri
|
|
|
:
|
Parivash Kordbacheh
|
|
|
:
|
S abbasi
|
|
|
:
|
Shahram Mahmoudi
|
| Originating Source
|
:
|
University of Tehran. Central Library and Documentation Center
|
| |